In one of the most exciting books in recent years, a german doctor describes numerous detailed patient cases to present the infectious parasite Toxoplasmosis as an mostly overlooked cause of certain – previously untreatable – diseases.

Dr. Uwe auf der Strasse – the hero-physician of 2019

Dr. Uwe auf der Strasse (abbreviation here: UadS) is a very special physician:

starting from the case of a woman who has been ill for 50 years and who was temporarily significantly improved with a special antibiotic (clindamycin), he was able to identify the underlying infection being Toxoplasmosis, worked up the scientific literature on Toxoplasmosis, successfully treated 150 similar patients and thus gave us a very detailed picture of one disease that is almost always misinterpreted as Lyme disease, rheumatism or chronic fatigue syndrome or fibromyalgia in patients that have not been successfully treated so far.

The book is yet only available in german:

The Toxoplasmosis Handbook: A parasite deceives medicine and makes us sick – Detect and treat Toxoplasma gondii

This book is actually a good scientific approach to real live medicine

In the book Dr. UadS presents 15 cases (10 with antibodies, 5 without antibodies) to work out the clinical features of the disease.

In his office  – he reports – he now has 150 successfully treated cases.

He also shows about 100 scientific studies to scientifically prove the ideas about toxoplasmosis presented in his book.

This book is a milestone: science and practice together, plus a lot of actually healed patients. Unprecedented! Bravo and thank you very much, dear colleague!

Dr. Uwe auf der Strasse – in a documentation made from German TV (not longer available)

a parasite has so far deceived us all

Toxoplasma is a unicellular parasite, similar to Babesia or Malaria. According to Wikipedia, 50% of all people in Germany are affected, the older ones up to 70%.

The parasite occurs in several forms

The tachyzoite is the official vegetative form, but the body forms antibodies in about 70% of the cases, which pass with long-term infection.

Wikipedia: From DPDx Image Library

In the human body the tachyzoite transforms into the spore form bradyzoite, which multiplies much more slowly and experiences a change in the cell membrane so that the human immune system no longer recognizes this “spore”.

We currently have no antibody diagnostics against the bradyzoites and so the disease can no longer be detected in the case of prolonged infection. Bradyzoites live above all in muscle cells and in the brain.


Yolanda Hadid, Dr. Simon Yu, Dr. Kinderlehrer and LYME

Yolanda Hadid’s heartbreaking book about her lime story

I am just hearing the audible of this true story of a famous US-TV-personality suffering lyme. 

To this moment I just have read about half the book so I do not know what actually improved her, but:

It seems rather obvious to me that her main problems are not borreliosis but are rather associated with bartonella and toxoplasmosis and especially her unwillingness to this point to do her teethwork (metals, root-canals + cavitations). Most rich people have gold in their mouth, often it contains palladium which leads to higly destructive problems. We more often than not find amalgam fillings underneath gold crones –> it is allowed to do such sloppy dental work!

As a horse lover she will be full of horse-herpes-virus and tons of parasitic worms, so Dr. Simon Yu in St. Louis could be s.o. who actually could improve her a lot – especially because Simon insists in getting the teeth done.

Dr. Simon Yu is so far the only physician that I know who has completely cured now 4 ALS-Patients, mainly with the help of his great dental surgon Dr. Steward Moreland who has turned in this collaboration to be a master in working up cavitations.

Dr. Friedrich Douwes, St. Georg Klinik, Bad Aibling & his beloved wife Renate Douwes

We have nearby (200km) a Clinic that actually cures Neuroborreliosis with heat. Dr. Friedrich Douwes is the accidental inventor of this technique, having treated US cancer patients with hyperthermia that improved marvellously with their lyme Symptoms.

Here is an Australian TV-Documentation about severely shakened neuroborreliosis patients that got cured in St. Georg Clinic in Bad Aibling Germany using 43° Hyperthermia.

I really belief that you can only cure borrelia with High-Temperature-hyperthermia (43°), never with antibiotics (or moderate Hyperthermia < 41°).

If anyone is seriously interested then put following article “why you can cure borreliosis with hyperthermia” of my german website through the google translator.

Maybe Disulfiram is the answer, I may refer to the work of Dr. Dan Kinderlehrer / Denver –> following Interview is the most precise and helpfull.

now back to Toxoplasmosis


Toxoplasmosis-Questionair – Score

the symptoms are very clear and create a good to memorize picture.

The percentage % behind a symptom refers to the percent of Toxo-patients presenting that symptom

“A” symptoms

  • great tiredness and exhaustion due to minimal effort, high need for sleep 100%
  • strong muscle pain, minimal exertion overworked and it takes days to relax: 100%
  • Concentration disorders: 93%
  • Sweating, especially At night 78%
  • Shortness of breath with little exertion, fast high pulse with exertion, feeling of pressure on the heart or chest, especially with exertion. Typical: previous examinations by a cardiologist 67% and / or pulmonologist. Cause: Infection of the heart muscle or diaphragm
  • Listlessness 63%
  • IgG against toxoplasm 60%

“B” symptoms

  • Irritability 59%
  • Visual disturbance, blurred vision, unclear vision – without an eye CH: 44%
  • Dizziness 37%
  • Depression 41%
  • Fears 33%

“C” symptoms

  • Morning stiffness 30%
  • Water retention (especially of the hands + feet): 33%
  • Sleep disorders 38%
  • Coordination disorder, runs against objects, gait insecurity
  • Abdominal pressure
  • headache
  • joint pain
  • Lymph node swelling


Do you suffer Toxoplasmosis?

if no more than 3 of the A symptoms are present and the other symptoms are normal, then there is probably no toxoplasmosis.

If there are at least 3 A symptoms and 3 from B / C, there is probably toxoplasmosis. TIREDNESS was the leading symptom that was always present in all reported cases.


Laboratory tests are often negative

Since the IgG antibodies (which only exist against the tachyzoite form) are not available in 40% of the patients, there is no absolutely reliable diagnosis.

According to UadS, the low number of CD8 NK cells (CD3-CD57+) is still the most specific symptom, which we also find most specific in chronic Lyme disease sufferers:

In the case of negative IgG, the toxoplasmosis LTT is often still indicative.

It is not clear why the CD45 + CD8 + CD56 + CD57 + CD3- cells are dropping. -> these are specific killer cells that in chron. Lyme disease drop below 100 and it seems that this lab value is the most specific criteria for achronic Lyme disease.

Unfortunately not measurable in Austria, we send it to the BCA or the Arminlabs, IMD Berlin also makes this diagnosis.


According to Dr. UadS these symptoms can be misdiagnosed with following diseases

  • B12 deficiency, foolic acid deficiency, iron deficiency, VitD deficiency, EBV, CMV, TBE – infections
  • Lyme disease: typical: severe joint problems that hike. Rarely sweats during the day.
  • Babesiosis: typical: relapsing fever such as malaria, punctiform skin bleeding
  • Chronic fatigue syndrome or myalgic encephalomyelitis -> specific metabolic laboratory changes (PNAS 2016) – Caution: these are very sensitive patients, you have to reduce medication to halve
  • Fibromyalgia (tender points, no neurological side effects)
  • somatoform pain processing disorder (increased sensitivity)
  • Heart disease – CHD
  • Bronchial asthma and COPD
  • chron. Gallbladder inflammation


Treatment fo Toxoplasmosis

Dr. UadS “tests” with clindamycin 3 x 300 – 2 x 600.

If the symptoms improve markedly, a specific parasite combination therapy with Pyrimethamine is used. This is a drug used for Malaria, Pneuocystis carinii and Babesia.

UadS combines Pyrimethamine

  • with sulfadiazine + calcium folinate, and in cases of intolerance,
  • combinations with clindamycin
  • or clarithromycin.

The treatment scheme is good deduceable from the presentation of the casuistics in his book and every physician should be able to follow it (I have compacted his scheme below).

course of treatment

Dr. auf der Strasse is a thoroughly systematic and structured doctor. For this reason, he lets the patients fill out a questionnaire for each (intermediate) examination and evaluates the symptoms. This is then shown graphically for the cases:

Case Nr 11 in the book of Dr. Uwe auf der Strasse


the course of treatment is spectacular and after 6 weeks most patients are well, even after 50 years of illness (!!!!!!)

Toxoplasmosis Case 6 from the book by Dr. from the street


soooo great – real clinical research at last

In our real daily praxice we all have the problem: we sit in front of suffering patients who expect real working solutions from us. And we do what we have studied. If the patient does not quite fit, we still do that. But if our treatment does not really help?

Just listen into the book of Yolanda Hadid: everyone sells her treatment, noone really has the perfect clue, its just try and error!

What a pain!!! Also for me – the physician: this feeling of uselessness and incapability is nearly killing me and is the basis of my now nearly 280 extra educational courses I did in the last 20 years!

The German Society for Neurology still diagnoses by means of ELIZA (50% error rate) and rejects the LTT as unscientific and describes chronic neuroborreliosis simply as a fairy tale, “since you came over every borrelia infection with a 3-week doxycyclin course”

Such experts are of no use for our praxis and actually a big embarressment for this haughty and complacent Professors that hinder progress and research.

How is this possible that these people in charge – the Neurologists – ignore the suffering of such patients?  Everyone can talk to the patients in the BCA or the St. Georg Clinic – or read the book of Yolanda!

This is why I respect this book of Dr. Uwe auf der Strasse so much: it is a pleasant and modest counterpoint: after reading the first 100 pages of this book, I have the feeling that I know this disease well and can also recognize it.

His procedure using “key symptoms” is realistic and practical and could serve us perfectly for all our difficult, chronic infection patients!

I dream of some clinical repertory in which you can get an exact list of all potential infectious agents by simply entering the 10 main complaints of the patient.

I would like to recommend the book to every doctor with chronic patients


finally: Evan Hirsch – Bartonellose

in this context I would definitely like to refer to another clinical author from the USA: Dr. To point out Evan Hirsch, who in his podcast (narrated by the great Scott Foresgren) and in his book emphasizes the symptoms of Bartonellose very clearly, I also wrote an article about Bartonellosis and Evan Hirsch.

Evan also thinks that the Borrelia mainly triggers wandering joint pain, but the Bartonella especially a violent burning of the legs and soles of the feet, together with a lot of central neurological complaints.


Antibiotic treatment according to Dr. Uwe auf der Strasse

Antibiotic treatment according to Dr. Uwe auf der Strasse

Dr. Uwe says: you can’t heal toxoplasma, just mitigate and keep them calm

Relapses are programmed, you have to get back to them as quickly as possible and therefore start AB therapy again as soon as possible, the relapses are then becoming rarer and easier – inform patients about them!

Dr. Uwe is more and more going to prescribe a weekly changing cure, because the Toxos come back after about 7-10 days under each AB.

initial Test-Treatment

Clindamycin 2-3 x 300mg (sensitive patients 2 × 300 or even only 2 x 150mg) -> for 1-2 weeks. Looses effect after 1-2 weeks, therefore rotating concept

Parasite treatment min 4 weeks up to 12 weeks

  • Pyrimethamine 2 x 25mg + Calc-Folinate approx. 7.5mg

this is the basic medication that needs an additional Antibiotic rotating all 5 days 

  • Sufadiazin 4 × 500
  • or Clinda 2 x 600
  • or Clarithro 2 × 500

then -> again with sulfa 

2nd line also as a companion AB for Pyrimethamine: cotrimoxazole 2 x 960 | Spira 1.5mio 4 × 1 to 3 × 2 (this without Pyri) -> change after 5d


Medications / Name and Pack-Size and Price (in Austria)

  • Dalacin C 300mg Kps OP1/30 OP1/16 – ca 14,-
  • Clindamycin MIP 300/600mg  OP1/16 – ca 14,- OP1/32 24,-
  • Daraprim (Pyrimethamine) 25mg Tbl, OP1/30 (Schweiz) – ca 10,-
  • Sulfadiazin 500mg  Heyl Tabletten OP1/500 – ca 50,-
  • Calcium Folinat EBEWE 15mg OP1/20 – ca 80,-
  • Clarithromycin 500 OP1/14 – ca 10,-

so it’s actually a rather cheap treatment, most expensive is Folic-Acid, the vitamin. Most patients are fine within 6-10 weeks as Dr UadS shows with his detailled case studies (see pictures above).



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